Cannabis And Its Active Ingredient


The medicinal consumption of cannabis preparations (Cannabis sativa L.) has increased dramatically in recent years, and anticoagulant effects, There is significant evidence in the scientific and clinical literature about the therapeutic power of such developments in the treatment of the symptoms of various diseases. However, it is necessary to take into account some important factors to optimize their possible therapeutic benefits and reduce their possible side effects. Marijuana is a plant with a great diversity of chemo types, each of which contains different proportions of active ingredients (cannabis).
Therefore, when a medicinal cannabis preparation is consumed, it is necessary to know its composition in cannabis, especially the two most relevant: Δ 9 -tetrahedron (THC) and cannabis (CBD). THC acts through specific receptors located on the surface of our cells, specifically the CB 1 cannabis receptors (very abundant in the central nervous system and responsible for the neurological effects of THC) and the CB 2 cannabis receptors (very abundant in the immune system and responsible for the anti-inflammatory effects of THC). CBD binds with very low affinity to said CB 1 and CB 2 receptors, but exerts, through alternative mechanisms, anti-inflammatory
In addition to preventing some unintended psychoactive consequences of THC such as psychosis, anxiety, and in coordination. Therefore, it is usually recommended that medicinal cannabis preparations have a balanced composition of THC and CBD, although with different ratios depending on the disease to be treated.
The cannabis content of a cannabis preparation depends on factors such as the race of the plant, its form of culture and the extraction technique. It is, of course, essential that the development to be used, in addition to having a known composition of THC and CBD, does not contain heavy metals, pathogenic microorganisms (bacteria and fungi), pesticides or other components that may be harmful to health.It is evident that cannabis is not a panacea, but it does have therapeutic properties for the symptomatic treatment of some diseases. These include several chronic pain, motor disorders associated with multiple sclerosis, cachet in cancer or AIDS, vomiting and nausea associated with ontological chemotherapy, seizures in childhood epilepsy and gastrointestinal inflammatory diseases.

The Patients

As in the case of any other medication, the person who wishes to use medicinal cannabis preparations can be from someone who ignores everything about cannabis to an accomplished expert in the field. In this sense, the knowledge of medical cannabis is evolving very quickly, and the fact that the patient has at least some notions about it is important to consume it correctly and responsibly. There are numerous publications to help acquire such knowledge, also, logically, the advice that can be provided by specialized health professionals (doctors, psychologists, nurses …) who are trained to do so.

Health Professionals

It is highly recommended that the patient request the assistance of a doctor or other health professional. It must be borne in mind, however, that many health professionals are unaware of the existence of the endocrinologist system in our bodies and the possible therapeutic applications of cannabis. This is due, in part, to the fact that this knowledge is relatively recent and also, perhaps, to the prejudices or stigmas that have accompanied the use of the plant for recreational purposes. In any case, this situation is progressively changing as there are numerous specialized publications on this subject. Some associations, such as the OECM (Spanish Observatory of Medicinal Cannabis) or the SEIC (Spanish Society of Research on Cannabis), can provide in our country medical cannabis advice to any professional who wants it. Also, the IACM (International Association for Cannabis Medicines) has a very detailed and updated electronic portal about the possible therapeutic uses of cannabis and cannabis.

It is highly advisable to inform the usual specialist doctor of the intention to use cannabis for medicinal purposes so that you can correctly evaluate the patient’s clinical evolution, drug interactions, etc. This is recommended even if the specialist is unaware of the possibility of using cannabis medicinally.

Many associations of medical cannabis patients have a medical service that can issue a certificate to justify, before the authorities, the consumption for medical reasons of preparations of the plant. In turn, this service can act as an interlocutor with the usual doctor who is treating the patient.

Summary Of Recommendations For The Patient

 Before self-medication with cannabis consult a trusted doctor and inform your usual doctor. If it lacks knowledge about the medicinal use of cannabis, download this document and give it to them.

Consulting with your doctor before using medicinal cannabis is especially crucial if you are pregnant or intend to be pregnant and in the case that you suffer from a psychiatric disorder, as well as if you are using cannabis and experience some Worrying side effect. Adolescence is also a period of high vulnerability to the unwanted neurological impact of marijuana.

Remember the existence of therapeutic cabinets in various associations specialized in medicinal cannabis. They are to advise you on your correct treatment with cannabis, for example in routes of administration, doses, compositions, etc.

The medicinal cannabis preparation that you are going to use must have reliable analyzes and certifications on its quality and form, as well as on the absence of toxic products.

Cannabis is a very safe medicine (it is not toxicity, it is not mutagen, and it is not lethal due to overdose …), but apparently, it is not harmless, and it has side effects (especially psychoactive ones) that should be minimized. Be well informed about them before their use, and also consult if there may be contraindications or interactions with your usual medication.

Administration Of Cannabis.

Given the growing number of inquiries received about the possibility of injecting cannabis instrumentally, and given the dire consequences that could result from such act, the Spanish Observatory of Medicinal Cannabis (OECM) wants to clarify the following:

The currently available cannabis products are prepared to be administered sub-lingual or orally through the use of oils or capsules, rectally via suppositories, inhaled by vaporizers or through the skin for topical use with creams or oils. NONE of the medicinal cannabis products that we have at our disposal have been designed to be administered by means other than those exposed.

For a product to be “injected,” either subcutaneously, intramuscular, intravenously or “instrumentally,” it must be designed taking into account fundamental pharmacological factors, such as the bio compatibility of the solvent used. Non-bio compatible solvents could trigger toxic reactions with unpredictable consequences.

Inject able products must also be sterile. Otherwise, the risk of bacteriological contamination is very high, which could lead to an infection in the surrounding tissues, which could trigger generalized sepsis that could put the patient’s life at risk.

The injection technique itself also involves significant risks when highly qualified health personnel do not perform it in invasive techniques. These procedures are usually supported by imaging techniques (such as MRI or ultrasound) that allow absolute control of the needle trajectory, and avoid complications such as the appearance of illnesses, perforation of nearby organs, injection of the product within a blood vessel or administration of the product outside the tumor, among others.

Another serious consequence would be the breakage of the tumor structure, which could allow the extrapolation of tumor cells into the bloodstream and other tissues, with the serious risk of causing the appearance of metastases in other organs.